Overview
Invitae Multi-Cancer Panel
The Invitae Multi-Cancer Panel analyses genes that are associated with a hereditary predisposition to adult-onset cancers across major organ systems, including breast, gynecologic, endocrine, skin and brain/nervous system.
Adult-onset hereditary cancers are genetically heterogeneous. Broad panel testing allows an efficient evaluation of many potentially relevant genes from a single clinical indication.
Nearly half of patients with a BRCA1 or BRCA2 genetic variant do not have a suggestive family history, and knowing their status before a breast cancer diagnosis leads to better survival rates. For patients who test negative for pathogenic variants, Invitae can provide a Tyrer-Cuzick score for a more complete picture of risk.
Who It May Suit
This test may be appropriate for individuals with a personal and/or family history of cancers across multiple organ systems. Features that suggest a hereditary cancer syndrome include:
- Cancer diagnosed at an unusually young age
- Different types of cancer that have occurred independently in the same person
- Cancer in both organs of a set of paired organs (for example both kidneys or both breasts)
- Several close blood relatives with the same type of cancer
- Unusual cases of a specific cancer type (for example breast cancer in a man)
Test Options
- Multi-cancer panel (84 genes)
- Most common cancers panel (47 genes)
- Breast and gynecological cancer panel (28 genes)
- Prostate cancer panel (16 genes)